منابع مشابه
Study of Long Noncoding RNA FER1L4 and RB1, as Its Competing Endogenous RNA Network Target Gene, in Breast Cancer
Introduction: Breast cancer is the second most common cause of cancer-related death among females, which requires an exploration for markers to propose a more specific categorization of this cancer. Long noncoding RNAs (lncRNAs), the main subset of noncoding transcripts, are involved in tumorigenic processes. In this study, we investigated the expression of the fer-1–like family member 4 (FER...
متن کاملDysregulated Expression of Long Non-Coding RNA MINCR and EZH2 in Colorectal Cancer
Background: As critical regulators, lncRNAs have attracted attention from researchers for diagnostic, prognostic, and therapeutic purposes in human carcinogenesis via interfering with mRNAs such as EZH2. Nevertheless, the potent roles and molecular mechanisms of these RNAs in CRC are not clearly known. Methods: In this study, the tissue expressions of lncRNA MINCR and EZH2 mRNA between colorect...
متن کاملLong Non-coding RNA ZEB1-AS1 Promotes Tumorigenesis and Metastasis in Colorectal Cancer
Emerging evidence implicates that a large fraction of human genome was transcribed but the transcripts known as long non coding RNA are not translated into proteins. They are contributing in different cellular processes, including cellular proliferation and apoptosis. LncRNAs were found to play critical roles in many diseases and act as key regulators in malignancies. In this study, we investig...
متن کاملHigh expression of long noncoding RNA AB073614 in colorectal cancer patients and its clinical significance
More and more studies have suggested that long non-coding RNAs (LncRNAs) are involved in different physiological or physiopathologic processes including the development of cancer. Previous studies have suggested long noncoding RNA AB073614 (lncRNA AB073614) is involved in ovarian cancer and glioma, but its role in colorectal cancer (CRC) is still unclear. A study was thus performed to examine t...
متن کاملNovel long noncoding RNA GACAT3 promotes colorectal cancer cell proliferation, invasion, and migration through miR-149
Aim To explore the expression and clinical significance of long noncoding RNA (lncRNA) gastric cancer-associated transcript 3 (GACAT3) in human colorectal cancer (CRC). Methods Expression of GACAT3 in CRC tissues and cell lines was measured using quantitative real-time PCR. CCK-8 and colony formation assays were used to assess the effect of GACAT3 on CRC cell line proliferation. Transwell inv...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2019
ISSN: 1582-1838,1582-4934
DOI: 10.1111/jcmm.14209